Product Name: S-Acetyl-L-Glutathione (SAG)
CAS No.: 3054-47-5
Appearance: White or Off white crystalline powder
Molecular weight: 349.36
Assay: 98%~101%
Synonym: N5-((R)-3-(Acetylthio)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine, SAG
Country of Origin: China
Product Description:
S-Acetyl-L-Glutathione penetrates into the mitochondrial membrane, helps maintain its integrity and function, and crosses the blood-brain barrier, allowing it to directly detoxify and protect the brain. Acetylated glutathione greatly improves its ability to remain intact in the intestine and allows higher concentrations to be absorbed into the bloodstream, better anti-aging.
Specification Sheet:
| ITEMS |
SPECIFICATIONS |
| Identification |
Positive |
| Appearance |
White or Off white
crystalline powder |
| Lose on drying |
≤0.5% |
| Residue on ignition |
≤0.2% |
| Total Heavy metals |
≤10ppm |
| Ammonium |
≤200ppm |
| Chloride |
≤200ppm |
| Sulfate |
≤300ppm |
| Iron |
≤10ppm |
| A cetone |
≤0.2% |
| Assay (S-Acetyl-L-Glutathione) |
98.0%~101% |
| GSH |
≤1.0% |
What is S-Acetyl -L-Glutathione?
S-Acetyl-L- glutathione is the acetylation product of reduced glutathione. The acetyl group is connected to the sulfur atom of cysteineto protect the molecule from oxidation in the digestive tract and prevent the decomposition of glutathione. , So that it can enter cells through the intestine and be directly absorbed. When the acetyl glutathione enters the cell, the acetyl group is degraded and removed, and the glutathione returns to its free form to play a role in the cell. On the other hand, there is no unpleasant sulfhydryl taste, which can quickly increase the level of reduced glutathione in the cell without increasing energy consumption. Compared with glutathione, acetyl glutathione is more stable in plasma, and has also been shown to be more effective in supplementing glutathione cell levels lacking due to viral infections.
The markers of oxidative stress and inflammation are the intracellular measurement of reduced glutathione
The role of tools. Reduction of oxidative stress markers is a measure of the effectiveness of reduced glutathione supplementation
A pilot study on 6 patients used oxidative stress markers to evaluate the effects of two dosage forms of glutathione: intravenous glutathione and oral acetyl glutathione for one week, with a dose of 1400 mg.
The researchers concluded that oral acetyl glutathione is equivalent to an equivalent dose of intravenous glutathione
(MICHAEL ASH published in REVIEWS in 2011)
Function
1) Anti-Aging and Easily Absorbed by Body
S-Acetyl L-Glutathione is a widely used glutathione and is a derivative and development of reduced glutathione. Acetylation refers to the process of transferring an acetyl group to a side chain group of an amino acid, and acetylation of glutathione is usually the attachment of an acetyl group to an active sulfur atom. S-Acetyl Glutatione is a form of glutathione that is more stable and easily absorbed by body than other forms on the market.
S-Acetyl Glutathione penetrates into the mitochondrial membrane, helps maintain its integrity and function, and crosses the blood-brain barrier, allowing it to directly detoxify and protect the brain. Acetylated glutathione greatly improves its ability to remain intact in the intestine and allows higher concentrations to be absorbed into the bloodstream, better anti-aging.
2) Protect Liver
S-Acetyl L-Glutathione is the most effective glutathione variant currently on the market. Glutathione is one of the most potent antioxidants that is naturally produced by the body ( and the only one that is intracellular ) and it has been shown to neutralize free radicals, detoxify the liver, and to improve the functioning of the immune system.
S-Acetyl L-Glutathione is an altered form with an attached acetyl function group. This greatly improves its ability to remain intact in the gut and allows a greater concentration to be absorbed into the bloodstream where it can take effect.It is a form of glutathione which is more stable in the human intestine and more easily absorbed by the body than other forms on the market.
Packaging Details
25 kg/drum, Net weight: 25kg, Gross weight: 28kg
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Company Profile:
* Our History:
Jingxin Nutra Co., Ltd focus on the development of R&D, manufacturing and exporting of nutrition & health ingredients since 2012. Our products are widely used in the fields of nutraceutical, dietary supplements, health food, beverage, cosmetic and pharmaceutical.
We have been proudly serving lots of contract manufacturers, brand customers and distributors in the global, and keeping very stable cooperation relationships with our customers.
* Main Market:
Europe, Russia, the Middle East, Asia, North America, South America etc. more than 50 countries and regions.
* Our Factory:
Our factory is constructed strictly in accordance with cGMP standard, it covers about 15000 square meters, with the clean workshop of 10000 square meters..
We have both production lines of plant extracts and chemicals.
-> Production lines of Plant Extracts:
We have 100,000 grade fine drying and packaging workshop to ensure that the products are not polluted.
• Extraction: It has a variety of extraction equipment, including multifunctional extraction, continuous countercurrent extraction, etc., which can be applied to the extraction of various medicinal materials, processing 8,000 tons of herb annually.
• Separation and refining: According to the product and process requirements, centrifugation, precision filtration, continuous ion exchange and other methods for separation and refining, to obtain high purity extract.
• Drying: With spray drying, freeze drying, vacuum drying, microwave drying.
-> Production lines of Chemicals:
It is based on enzyme catalysis technology to produce synthethic chemicals.The production lines are equipped with R&D center, pilot plant, chemical reaction workshop, biological fermentation workshop, clean workshop etc and meets production quality management of cGMP, FSSC22000 and HACCP.
* Main Products:
Glutathione, L-Theanine, L-Melatonin, Alpha Lipoic Acid , β-Nicotinamide mononucleotide (NMN), Coenzyme Q10, L-Carnitine Base, Selachyl alcohol, Beta Glucan, 3,3'-diindolylmethane (DIM), Ascorbic Acid (Vitamin C), Vitamin B12, Sweeteners etc.
Tongkat Ali Extract, Rutin, Fisetin, Milk Thistle Extract, Ginkgo Biloba Extract, Grape Seed Extract, Berberine HCL, Resveratrol, Monk Fruit Extract, Stevia Extract etc.
* Products Application:
Nutraceutical, dietary supplement, food additives, Beverage, cosmetics and feed additives etc.
* Certificates:
ISO, KOSHER, HALAL etc.
* Quality Control:
We adhere to the orientation of 'Quality first" and strictly control the whole production process meet cGMP standard.
Our quality inspection center is equipped with physical and chemical room, Ultraviolet analysis room, Atomic absorption room, Atomic fluorescence room, Gas chromatography room, High Performance Liquid Chromatography room, balance room, High greenhouse, calibration room, bacteria examination room, Reagent room, stability laboratory, sample room and central laboratory.
The main testing capabilities include loss on drying, Ash, density, TLC, solubility, optical rotation, Transmittance, heavy metals, Lead, Arsenic, Calcium, Mercury, PH, protein, amino nitrogen, Assay, Purity, Solvent residue, Pesticide residue. Microbial detection includes detection of total Plate count, coliforms, yeasts and molds, salmonella, staphylococcus aureus etc.
We strictly test all products from source to finished products to ensure it meet customer's requirements.
* Our Service:
We provide raw material ingredients, Premix blend and OEM are avaliable too.
We have decades of the experience in these fields, could offer considerate, timely and professional service.
If the quality do not complies with customer's specification, we will undertake the responsibility and give customer a full refund.
We hope to be your long-term partner for mutual benefit.
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