Wholesale Pure 99% 3, 3′ -Diindolylmethane for Anticancer Dim

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >98%
• Model NO.: 3 3′-Diindolylmethane 3 3′- diindole methane DIM
• Product Name: 3, 3′-Diindolylmethane
• Other Name 1: 3, 3′- Diindole Methane
• Other Name 2: Dim
• CAS No.: 1968-05-4
• Transport Package: 25kg/Fiber Drum
• Specification: 98%
• Trademark: JX Nutra
• Origin: China
• HS Code: 2933990099
• Production Capacity: 5mt/Month

Product Description

3,3'-Diindolylmethane (DIM), 98% DIM, 98% 3,3'-Diindolylmethane

 

Product Name	3,3'-Diindolylmethane (DIM), 3,3'- diindole methane, antitumor agent
Formal Name	3,3'-methylenebis-1H-indole, 3-(1H-Indol-3-ylmethyl)-1H-indole,  3,3′-Methylenedi(1H-indole)
CAS Number	1968-05-4
Synonyms	DIM
Molecular Formula	C17H14N2
Formula Weight	246.3
Purity	≥98%
Physical State	A crystalline solid
Solubility	Soluble in DMSO (200 mg/ml), ethanol (50 mM), chloroform, and methanol. Insoluble in water.
Storage	Store at 2~8° C
Melting Point	167° C
Shipping	Room Temperature; may vary elsewhere
Stability	≥ 2 years

Description of 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane):
3,3 '- diindole methane widely exists in natural plants of Cruciferae. It has important biological and pharmacological activities. It is also an effective radiation protector and mitigation agent. It stimulates ATM driven DDR like response and NF- κ B to function as a survival signal. 3,3 '- diindole methane can regulate signal pathways, such as Akt and NF- κ B and FoxO3 to inhibit tumor cell invasion, angiogenesis, proliferation and induce apoptosis. It can also inhibit estrogen induced gene expression and cause endoplasmic reticulum stress response. 3,3 '- diindole methane can change estrogen metabolism and antagonize estrogen and androgen receptor activities.

Specification Sheet of 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane):

ITEM	SPECIFICATION
Appearance	White or Off-white Crystalline powder
Loss on drying	≤2.0%
Residue on ignition	≤1.0%
Odor & Taste	Characteristic
Particle size	98% pass 80 mesh
Heavy metals	≤10ppm
Arsenic(As)	≤2ppm
Lead(Pb)	≤2ppm
Cadmium(Cd)	≤1ppm
Mercury(Hg)	≤0.1ppm
3,3'-diindolylmethane (DIM)	≥98.0%
Total Plate Count	≤1000CFU/g
Yeast &Mould	≤100CFU/g
Escherichia Coli	Negative
Salmonella	Negative

Function of 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane):
Cancer prevention, Reduce harmful estrogen, anti-aging
1.3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane) can help prevent and treat breast cancer and prostate cancer. Animal studies also found that 3,3 '- diindole methane can prevent the replication and proliferation of cancer cells. Moreover, 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane) can inhibit angiogenesis and prevent the formation of new blood vessels. Tumors need the growth of new blood vessels to provide nutrients necessary for tumor prosperity. By preventing the growth of new blood vessels, 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane) can therefore help eliminate tumors
2.3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane) helps to balance the sex hormone estrogen. When estrogen is decomposed in your body, it can form beneficial or harmful estrogen metabolites, and 3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane)an help your body decompose estrogen into beneficial types. Beneficial estrogen metabolites have antioxidant properties and help protect the heart and brain from free radical damage. Two indolmethyl methane also reduces the level of harmful estrogen metabolites, which is beneficial because they are associated with increased risk of obesity, breast cancer and uterine cancer.
 3.3,3'-Diindolylmethane (DIM, 3,3 '- diindole methane) helps the human body fight aging and promote the healthy balance of testosterone in the body. Testosterone supports energy, promotes a happy mood, and helps maintain healthy sexuality. In addition, zegligs pointed out that 3,3 '- diindole methane may have anti-aging effects and may help promote lean body weight. Combined with exercise, you can increase muscle mass.

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Company Profile:

* Our History:
Jingxin Nutra Co., Ltd focus on the development of R&D, manufacturing and exporting of nutrition & health ingredients since 2012. Our products are widely used in the fields of nutraceutical, dietary supplements, health food, beverage, cosmetic and pharmaceutical. 
We have been proudly serving lots of contract manufacturers, brand customers and distributors in the global, and keeping very stable cooperation relationships with our customers.

* Main Market:
Europe, Russia, the Middle East, Asia, North America, South America etc. more than 50 countries and regions.


* Our Factory:
Our factory is constructed strictly in accordance with cGMP standard, it covers about 15000 square meters, with the clean workshop of 10000 square meters..
We have both production lines of plant extracts and chemicals.

-> Production lines of Plant Extracts:
We have 100,000 grade fine drying and packaging workshop to ensure that the products are not polluted.
• Extraction: It has a variety of extraction equipment, including multifunctional extraction, continuous countercurrent extraction, etc., which can be applied to the extraction of various medicinal materials, processing 8,000 tons of herb annually.
• Separation and refining: According to the product and process requirements, centrifugation, precision filtration, continuous ion exchange and other methods for separation and refining, to obtain high purity extract.
• Drying: With spray drying, freeze drying, vacuum drying, microwave drying.

-> Production lines of Chemicals:
It is based on enzyme catalysis technology to produce synthethic chemicals.The production lines are equipped with R&D center, pilot plant, chemical reaction workshop, biological fermentation workshop, clean workshop etc and meets production quality management of cGMP, FSSC22000 and HACCP.



* Main Products:
Glutathione, L-Theanine, L-Melatonin, Alpha Lipoic Acid , β-Nicotinamide mononucleotide (NMN), Coenzyme Q10, L-Carnitine Base, Selachyl alcohol, Beta Glucan, 3,3'-diindolylmethane (DIM), Ascorbic Acid (Vitamin C), Vitamin B12, Sweeteners etc.

Tongkat Ali Extract, Rutin, Fisetin, Milk Thistle Extract, Ginkgo Biloba Extract, Grape Seed Extract, Berberine HCL, Resveratrol, Monk Fruit Extract, Stevia Extract etc.

* Products Application:
Nutraceutical, dietary supplement, food additives, Beverage, cosmetics and feed additives etc.

* Certificates:
ISO, KOSHER, HALAL etc.

* Quality Control: 

We adhere to the orientation of 'Quality first" and strictly control the whole production process meet cGMP standard.

Our quality inspection center is equipped with physical and chemical room, Ultraviolet analysis room, Atomic absorption room, Atomic fluorescence room, Gas chromatography room, High Performance Liquid Chromatography room, balance room, High greenhouse, calibration room, bacteria examination room, Reagent room, stability laboratory, sample room and central laboratory.
The main testing capabilities include loss on drying, Ash, density, TLC, solubility, optical rotation, Transmittance, heavy metals, Lead, Arsenic, Calcium, Mercury, PH, protein, amino nitrogen, Assay, Purity, Solvent residue, Pesticide residue. Microbial detection includes detection of total Plate count, coliforms, yeasts and molds, salmonella, staphylococcus aureus etc.

We strictly test all products from source to finished products to ensure it meet customer's requirements.

* Our Service:
We provide raw material ingredients, Premix blend and OEM are avaliable too.

We have decades of the experience in these fields, could offer considerate, timely and professional service.

If the quality do not complies with customer's specification, we will undertake the responsibility and give customer a full refund.

We hope to be your long-term partner for mutual benefit.