Natural Fisetin From Cotinus Coggygria Extract Smoke Tree for Anti Inflammatory Fisetin

• Customization: Available
• Certification: ISO, FDA, HACCP, Halal
• Assay Method: HPLC
• Model NO.: Fisetin Cotinus coggygria Extract Smoke Tree
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products
• State: Powder
• Extract Source: Cotinus Coggygria Smoke Tree
• Product Name: Fisetin
• CAS No.: 528-48-3
• Other Name: Cotinin,Fisetholz, Fietin, Fustel, Fustet, Viset
• Function 1: Anti-Inflammatory
• Function 2: Inhibit Prostaglandin
• Transport Package: 20kgs/Fiber Drum
• Specification: Fisetin 10%, 40%, 50%, 70%, 80%, 85%, 95%, 98%
• Trademark: JX Nutra
• Origin: China
• HS Code: 1302199099
• Production Capacity: 10000kgs/Month

Product Description

Product Name: Fisetin
CAS NO.: 528-48-3
Aassay: Fisetin 10%,40%,50%,70%,80%,85%,95%,98%
Botanical Name: Cotinus coggygria, smoke tree
Part Used: Branch
Chemical formula: C15H10O6
Other Names: Cotinin (not to be confused with Cotinine), 5-Deoxyquercetin, Superfustel, Fisetholz, Fietin, Fustel, Fustet, Viset, Junger fustik, 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxychromen-4-one

Specification Sheet of Fisetin 98%:

Product Name:	Fisetin	Latin Name:	Cotinus coggygria
Part Used:	Branch (without skin)	Extract Solvent:	Ethanol & Water
Country of Origin:	China	Drying Method:	Spray drying

 

ITEM	SPECIFICATION	STANDARD REFERENCED
Appearance	Yellow Powder	Visual
Odor	Characteristic	Sensory
Taste	Characteristic	Sensory
Particle size	98% pass 80 mesh	Sieve
Loss on drying	≤5.0%	2g/105ºC/5hrs
Ash	≤5.0%	2g/600ºC/5hrs
Heavy metals	≤10ppm	Colorimetric method
Arsenic(As)	≤1ppm	Atomic Absorption
Lead(Pb)	≤1ppm	Atomic Absorption
Cadmium(Cd)	≤1ppm	Atomic Absorption
Mercury(Hg)	≤0.1ppm	Atomic Absorption
Solvent Residue	≤5000ppm	Gas Chromatography
Pesticide Residuals	Meets USP<561>	USP<561>
Fisetin	≥98.0%	HPLC
Total plate count	≤1000CFU/g	ChP
Yeast & Mould	≤100CFU/g	ChP
E.Coli	Negative	ChP
Salmonella	Negative	ChP
S.aureus	Negative	ChP
Packing	Pack in paper-drums and two food grade poly bags inside. Net weight: 15kg~20kg/drum or depends on customer's requirements.
Storage condition	Store in a well closed place with constant low temperature and no direct sun light
Shelf life	Two years when properly stored.

Product Description:
Fisetin is an unique botanical polyphenol and flavonoid found in a wide variety of plants, fruits and vegetables including strawberries, apples, persimmons, onions and cucumbers. Fisetin is a plant pigment, imparting many fruits and vegetables, such as strawberries, with their characteristic color and appearance. Fisetin has a very similar molecular structure to the more popular plant flavonoid and dietary supplement Quercetin. Unlike Quercetin, however, Fisetin is a senolytic and perhaps one of the most powerful senolytics known.


Function:

1. Fisetin can inhibit prostaglandin
2. Fisetin can be used to improve rheumatism, dysentery, gastrological, hernia, abdominal distension, toothache,traumatic injures, and skin ulcer in clinical;
3. Fisetin can be used as anti-inflammatory and antiproliferative;

Pharmacology:
1. Inhibition of prostaglandin: It can inhibit the formation of prostatic cords in 3T3 mouse fibrocytes transformed by methylcholanthracene, and the half effective inhibitory concentration (ID50) is 42.0UM.
2. Enzyme inhibition: It can inhibit the whole sugar reductase in the rat lens, and the half effective inhibition concentration is 10-6M
3. Spasmolytic: The antispasmolytic effect of acetylcholine was 166% of that of papaverine in small intestine specimens of mice.
4. In animal studies, a team of Japanese and American researchers found that urushetin, found in vegetables and fruits, improves memory.


-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Company Profile:

* Our History:
Jingxin Nutra Co., Ltd focus on the development of R&D, manufacturing and exporting of nutrition & health ingredients since 2012. Our products are widely used in the fields of nutraceutical, dietary supplements, health food, beverage, cosmetic and pharmaceutical. 
We have been proudly serving lots of contract manufacturers, brand customers and distributors in the global, and keeping very stable cooperation relationships with our customers.

* Main Market:
Europe, Russia, the Middle East, Asia, North America, South America etc. more than 50 countries and regions.


* Our Factory:
Our factory is constructed strictly in accordance with cGMP standard, it covers about 15000 square meters, with the clean workshop of 10000 square meters..
We have both production lines of plant extracts and chemicals.

-> Production lines of Plant Extracts:
We have 100,000 grade fine drying and packaging workshop to ensure that the products are not polluted.
• Extraction: It has a variety of extraction equipment, including multifunctional extraction, continuous countercurrent extraction, etc., which can be applied to the extraction of various medicinal materials, processing 8,000 tons of herb annually.
• Separation and refining: According to the product and process requirements, centrifugation, precision filtration, continuous ion exchange and other methods for separation and refining, to obtain high purity extract.
• Drying: With spray drying, freeze drying, vacuum drying, microwave drying.

-> Production lines of Chemicals:
It is based on enzyme catalysis technology to produce synthethic chemicals.The production lines are equipped with R&D center, pilot plant, chemical reaction workshop, biological fermentation workshop, clean workshop etc and meets production quality management of cGMP, FSSC22000 and HACCP.



* Main Products:
Glutathione, L-Theanine, L-Melatonin, Alpha Lipoic Acid , β-Nicotinamide mononucleotide (NMN), Coenzyme Q10, L-Carnitine Base, Selachyl alcohol, Beta Glucan, 3,3'-diindolylmethane (DIM), Ascorbic Acid (Vitamin C), Vitamin B12, Sweeteners etc.

Tongkat Ali Extract, Rutin, Fisetin, Milk Thistle Extract, Ginkgo Biloba Extract, Grape Seed Extract, Berberine HCL, Resveratrol, Monk Fruit Extract, Stevia Extract etc.

* Products Application:
Nutraceutical, dietary supplement, food additives, Beverage, cosmetics and feed additives etc.

* Certificates:
ISO, KOSHER, HALAL

* Quality Control: 

We adhere to the orientation of 'Quality first" and strictly control the whole production process meet cGMP standard.

Our quality inspection center is equipped with physical and chemical room, Ultraviolet analysis room, Atomic absorption room, Atomic fluorescence room, Gas chromatography room, High Performance Liquid Chromatography room, balance room, High greenhouse, calibration room, bacteria examination room, Reagent room, stability laboratory, sample room and central laboratory.
The main testing capabilities include loss on drying, Ash, density, TLC, solubility, optical rotation, Transmittance, heavy metals, Lead, Arsenic, Calcium, Mercury, PH, protein, amino nitrogen, Assay, Purity, Solvent residue, Pesticide residue. Microbial detection includes detection of total Plate count, coliforms, yeasts and molds, salmonella, staphylococcus aureus etc.

We strictly test all products from source to finished products to ensure it meet customer's requirements.

* Our Service:
We provide raw material ingredients, Premix blend and OEM are avaliable too.

We have decades of the experience in these fields, could offer considerate, timely and professional service.

If the quality do not complies with customer's specification, we will undertake the responsibility and give customer a full refund.

We hope to be your long-term partner for mutual benefit.