Product Name: Milk thistle extract
Latin Name: Silybum marianum (L.)
CAS. NO.: 84604-20-6
Plant Source: Fruit
Specification: 10:1; 80%Silymarins; 30% Silybins
Appearance: Yellow brown powder
Test Method: HPLC / TLC
Description:
Silybum marianum is an annual or biennial plant of the Asteraceae family. This fairly typical thistle has red to purple flowers and shiny pale green leaves with white veins. Originally a native of Southern Europe through to Asia, it is now found throughout the world. Several scientific studies suggest that substances in milk thistle (especially a flavonoid called silymarin) protect the liver from toxins. Silymarin has antioxidant and anti-inflammatory properties, and it may help the liver repair itself by growing new cells.
Specification Sheet:
| Product Name: |
Milk Thistle Extract |
Latin Name: |
Silybum marianum (L.)Gaertn |
| Part Used: |
Seed |
Extract Solvent: |
Acetone |
| Country Origin: |
China |
| ITEM |
SPECIFICATION |
STANDARD REFERENCED |
| Physical |
Appearance |
Yellowish brown to yellow powder |
Visual |
| Odor & Taste |
Characteristic |
Organoleptic |
| Loss on drying |
≤5.0% |
2g/105ºC/5hrs |
| Suphated Ash |
≤0.5% |
2g/600ºC/5hrs |
| Solubility |
100mg Silymarin soluble in 10ml Methanol |
Visual |
| Particle size |
98% pass 80 mesh |
Sieve |
| Chemical |
Heavy metals |
≤10ppm |
Colorimetric Method |
| Arsenic(As) |
≤1ppm |
Atomic Absorption |
| Lead(Pb) |
≤2ppm |
Atomic Absorption |
| Cadmium(Cd) |
≤1ppm |
Atomic Absorption |
| Mercury(Hg) |
≤0.1ppm |
Atomic Absorption |
| Residue solvent (Acetone) |
≤0.5% |
Gas Chromatography |
| Residue solvents (Others) |
≤0.05% |
Gas Chromatography |
| Pesticide residual |
USP<561> |
USP<561> |
| Aflatoxins |
≤50ppb |
ChP |
| Assay |
Silymarin |
≥80.0% |
UV |
| Silybin A+B, Isosilibin A+B |
≥30.0% |
HPLC |
| Microbial |
Total microbacterial count |
≤1000CFU/g |
ChP |
| Yeast & Mould |
≤100CFU/g |
ChP |
| Escherichia Coli |
Negative |
ChP |
| Bile Tolerant Gram Negative Bacteria |
Negative |
ChP |
| P.aeruginosa |
Negative |
ChP |
| Staphylpcoccus Aureus |
Negative |
ChP |
| Salmonella |
Negative |
ChP |
| Else |
Packing |
Pack in paper-drums and two plastic bag inside. Net weight: 25kg/drum |
| Storage condition |
Store in a well closed place with constant low temperature and no direct sun light |
| Shelf life |
Three years when properly stored. |
| Non Irradiated, Non GMO |
Function:
1.Milk thistle P.E. provides hepatocellular protection by stablizing hepatic cell membranes.
2.Milk thistle P.E. alters the structureof the outer cell membrane of the hepatocytes in such a way as to prevent the penetration of the liver toxins into interior of the cell.
3.Silymarin has the stimulation effect on nucleolar polymerase A results in an increase in ribosomalprotein synthesis,and thus increase the regenerative ability of the liver and formation of new hepatocytes.
4.Silymarin as other actions include interruption of enterohepatic recirculation of toxins and regeneration of damaged hepatocytes.
Application:
1. Silymarin extract is widely used in medicine, health products, food and cosmetics;
2. Protecting liver cell membrane and improving the liver function;
3. Detoxification, reducing the blood fat, benefiting the gallbladder, protecting the brain and removing the free ra dical of body. As a kind of better antioxidant, it can clear free radical in human body, postpone senility;
4. Silymarin extract has the function of radiation hardening, arteriosclerosis preventing, and skin-aging
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Company Profile:
* Our History:
Jingxin Nutra Co., Ltd focus on the development of R&D, manufacturing and exporting of nutrition & health ingredients since 2012. Our products are widely used in the fields of nutraceutical, dietary supplements, health food, beverage, cosmetic and pharmaceutical.
We have been proudly serving lots of contract manufacturers, brand customers and distributors in the global, and keeping very stable cooperation relationships with our customers.
* Main Market:
Europe, Russia, the Middle East, Asia, North America, South America etc. more than 50 countries and regions.
* Our Factory:
Our factory is constructed strictly in accordance with cGMP standard, it covers about 15000 square meters, with the clean workshop of 10000 square meters..
We have both production lines of plant extracts and chemicals.
-> Production lines of Plant Extracts:
We have 100,000 grade fine drying and packaging workshop to ensure that the products are not polluted.
• Extraction: It has a variety of extraction equipment, including multifunctional extraction, continuous countercurrent extraction, etc., which can be applied to the extraction of various medicinal materials, processing 8,000 tons of herb annually.
• Separation and refining: According to the product and process requirements, centrifugation, precision filtration, continuous ion exchange and other methods for separation and refining, to obtain high purity extract.
• Drying: With spray drying, freeze drying, vacuum drying, microwave drying.
-> Production lines of Chemicals:
It is based on enzyme catalysis technology to produce synthethic chemicals.The production lines are equipped with R&D center, pilot plant, chemical reaction workshop, biological fermentation workshop, clean workshop etc and meets production quality management of cGMP, FSSC22000 and HACCP.
* Main Products:
Glutathione, L-Theanine, L-Melatonin, Alpha Lipoic Acid , β-Nicotinamide mononucleotide (NMN), Coenzyme Q10, L-Carnitine Base, Selachyl alcohol, Beta Glucan, 3,3'-diindolylmethane (DIM), Ascorbic Acid (Vitamin C), Vitamin B12, Sweeteners etc.
Tongkat Ali Extract, Rutin, Fisetin, Milk Thistle Extract, Ginkgo Biloba Extract, Grape Seed Extract, Berberine HCL, Resveratrol, Monk Fruit Extract, Stevia Extract etc.
* Products Application:
Nutraceutical, dietary supplement, food additives, Beverage, cosmetics and feed additives etc.
* Certificates:
ISO, KOSHER, HALAL etc.
* Quality Control:
We adhere to the orientation of 'Quality first" and strictly control the whole production process meet cGMP standard.
Our quality inspection center is equipped with physical and chemical room, Ultraviolet analysis room, Atomic absorption room, Atomic fluorescence room, Gas chromatography room, High Performance Liquid Chromatography room, balance room, High greenhouse, calibration room, bacteria examination room, Reagent room, stability laboratory, sample room and central laboratory.
The main testing capabilities include loss on drying, Ash, density, TLC, solubility, optical rotation, Transmittance, heavy metals, Lead, Arsenic, Calcium, Mercury, PH, protein, amino nitrogen, Assay, Purity, Solvent residue, Pesticide residue. Microbial detection includes detection of total Plate count, coliforms, yeasts and molds, salmonella, staphylococcus aureus etc.
We strictly test all products from source to finished products to ensure it meet customer's requirements.
* Our Service:
We provide raw material ingredients, Premix blend and OEM are avaliable too.
We have decades of the experience in these fields, could offer considerate, timely and professional service.
If the quality do not complies with customer's specification, we will undertake the responsibility and give customer a full refund.
We hope to be your long-term partner for mutual benefit.
Audited Supplier 
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